Altered steroidogenesis in whole-ovary and adrenal culture in cycling rats
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Altered steroidogenesis in whole-ovary and adrenal culture in cycling rats by Ezra Berman

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Published by Environmental Protection Agency in [Washington, D.C.? .
Written in English

Subjects:

  • Rats as laboratory animals -- Research -- United States.,
  • Ovaries -- Research -- United States.

Book details:

Edition Notes

Other titlesAltered steroidogenesis in whole ovary and adrenal culture in cycling rats
StatementEzra Berman and John W. Laskey.
ContributionsLaskey, John W., United States. Environmental Protection Agency
The Physical Object
Pagination1 v.
ID Numbers
Open LibraryOL17110810M

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We also reported that phenolsulfonthalein present in many culture media formulations altered the steroid production profile in minced whole-ovary cultures from all stages of the estrous cycle evaluated, but that the difference was most prominent in by:   Berman E, Laskey JW. Altered steroidogenesis in whole-ovary and adrenal culture in cycling rats. Reprod Toxicol. ; – Bhattacharya N, Dufour JM, Vo MN, Okita J, Okita R, Kim KH. Differential effects of phthalates on the testis and the liver. Biol Reprod. ; –Cited by:   Our ongoing studies indicate that several other PEs that have been shown to inhibit testicular steroidogenesis also induce midpregnancy abortions in the SD rat. In light of the results reported here, it is noteworthy that phthalate exposures also have been associated with reproductive effects in women and nonhuman by: Berman E, Laskey JW. Altered steroidogenesis in whole-ovary and adrenal culture in cycling rats. Reprod Toxicol. ; – Blount BC, Milgram KE, Silva MJ, Malek NA, Reidy JA, Needham LL, et al. Quantitative detection of eight phthalate metabolites in human urine using HPLC-APCI-MS/MS. Anal Chem. a; –Cited by:

  Lipoproteins are complex particles containing a lipid core surrounded by amphiphilic proteins and phospholipids (see Chap. ). Low-density lipoprotein (LDL; density = – g/mL) is the predominant cholesterol and cholesteryl ester carrier in human plasma and provides cholesterol to cells for membrane synthesis and as substrate for steroidogenesis in steroidogenic organs such as the ovary. 78 High-density lipoprotein . To detect steroidogenic alterations in cycling and pregnant rats following cadmium exposures in vivo (at 3 or 5 mg/kg as a single s.c. dose) and in vitro (from 0 through microM Cd(2+)) whole. 1 2 This page intentionally left blank. 3 4 Draft Steroidogenesis DRP May Crossref | PubMed | Scopus () | Google Scholar See all References, 21 x 21 Berman, E. and Laskey, J.W. Altered steroidogenesis in whole-ovary and adrenal culture in cycling rats. Reprod Toxicol. ; 7: –Cited by:

adrenal culture in cycling rats. Altered steroidogenesis in whole-ovary and adrenal culture in cycling rats Whole-ovary culture is recommended as an in vitro test for chemicals suspected. Furthermore, the local effects that are essential for normal ovarian physiology are dependent on the endocrine, paracrine, and autocrine actions of E2, P4, and androgens. In most mammals (including humans and mice), ovarian steroidogenesis occurs according to the two-cell/two-gonadotropin theory.   In response to increasing concerns regarding the potential of chemicals to interact with the endocrine system of humans and wildlife, various national and international programs have been initiated with the aim to develop new guidelines for the screening and testing of these chemicals in vertebrates. Here, we report on the validation of an in vitro assay, the HR steroidogenesis assay, to Cited by: References and Sources for Chapter Five – Screening and Testing Berman, E., and J. Laskey, “Altered steroidogenesis in whole-ovary and adrenal culture in cycling rats,” Reproductive Toxicology, 7, , pp. Briand P, and A.E. Lykkesfeldt, “Long-term cultivation of a human breast cancer cell line, MCF7, in.